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Efficiently Determine Clenbuterol, Ractopamine, and Phenolethanolamine in Meat

SUNNYVALE, CA (April 2014) — Thermo Fisher Scientific has developed a high-performance liquid chromatography (LC) method that simplifies determination of clenbuterol, ractopamine, and phenolethanolamine in meat using on-line solid-phase extraction (SPE) and ultraviolet absorbance detection. Application Brief (AB) 154: Rapid and Sensitive Determination of Clenbuterol, Ractopamine, and Phenolethanolamine in Meat demonstrates that this method, performed using a dual rapid separation LC system controlled by data management software, achieves method detection limits equivalent to those obtained by mass spectrometry (MS). Additionally, this approach offers the advantages of full automation, the absence of operator influence, time savings, and strict process control.

Clenbuterol, ractopamine, and phenolethanolamine—substances that have been extensively used as growth stimulants in farm animals and by athletes seeking enhanced performance—can cause adverse side effects in humans. As a result, these substances have been banned as a food/feed additive in many countries. Food safety regulators need an efficient way to test for clenbuterol, ractopamine, and phenolethanolamine in meat. The AB 154 on-line SPE approach provides a cost-effective solution.

This application brief and many others can be found under the Documents tab.


About Thermo Fisher Scientific

Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, with revenues of $17 billion and 50,000 employees in 50 countries. Our mission is to enable our customers to make the world healthier, cleaner and safer. We help our customers accelerate life sciences research, solve complex analytical challenges, improve patient diagnostics and increase laboratory productivity. Our four premier brands – Thermo Scientific, Life Technologies, Fisher Scientific and Unity Lab Services – offer an unmatched combination of innovative technologies, purchasing convenience and comprehensive support. For more information, please visit www.thermofisher.com.