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Natural Sources Offer New Opportunities for Drug Discovery

During the last half of the 20th century, small molecule pharmaceutical drug discovery was typically the result of modifying a known molecule with the desired pharmacological activity through rational design or combinatorial chemistry. However, in recent times, drug discovery chemists have found and continue to discover new drug candidate opportunities in natural products. Some of that has come from studying the use of herbal products in undeveloped countries and some from the discovery of ancient treatments such as Traditional Chinese Medicines.

Regardless of the complexity of the matrix from which the pharmacologically active ingredient is extracted, the Thermo Scientific IC, RSLC and LC/MS system solutions offer the analytical drug discovery chemist the tools to find the needle in the haystack.