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RFIC-Eluent Generation

Eluent Generation—A Major Component of Reagent-Free IC

Eluent generation prevents baseline shift, increases sensitivity, improves resolution, and ensures consistent peak integration. A range of Thermo Scientific Dionex EGC cartridges are available for the production of hydroxide, carbonate, bicarbonate and methanesulfonic acid eluents. Eluent generation eliminates the need to handle acids and bases traditionally required for the preparation of IC eluents, and allows chromatographers to run a full range of gradient and isocratic separations more effectively than hand-made eluents.

  • Automatic production of high-purity eluents for isocratic and gradient separations on Thermo Scientific Dionex ICS-5000+ and ICS-2100 systems
  • Outstanding run-to-run reproducibility week after week
  • Elimination of acid and base handling
  • Longer lasting pumps because they encounter only deionized water
  • Supports both Analytical and Capillary flow rates
  • Supports HPIC system pressures up to 5000 psi (34.5 MPa, Dionex EGC Capillary and EGC 500 only)


Electrolytic Eluent Generation Process

Dionex EGC III and EGC 500 cartridges support a concentration range of 0.1–100 mM (0.1–80 mM EGC III LiOH, 0.1-15 mM EGC 500 K2CO3) at 1.0 mL/min. The KOH, NaOH and LiOH cartridges support a maximum of 25% methanol. The K2CO3 and MSA cartridges are not solvent-compatible.

Dionex EGC (Capillary) cartridges support a concentration range of 0.1–200 mM at 0.010 mL/min and a flow rate range of 0.001–0.030 mL/min. The Dionex EGC-KOH (Capillary) cartridge supports a maximum of 25% methanol. The Dionex EGC-MSA (Capillary) cartridge is not solvent-compatible.