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Bio Columns

Biological separations often require unique chemistry to provide high resolution, high efficiency separations. Dionex offers a variety of columns for proteins, peptides, carbohydrates, nucleic acids, and more.

Protein Columns

Dionex offers polymer-based columns for the separation of proteins by ion exchange chromatography. Each of these ultra-high efficiency columns provides sufficient resolution to allow separation of protein isoforms that, in many cases, differ by only a single amino acid residue.

Carbohydrate Columns

The Dionex CarboPac family of columns offers a selection of columns, each optimized for a different class of compounds. The Dionex CarboPac Column Selection Guide can help you determine the best column to use for your specific application need. Combined with pulsed amperometric detection (PAD)—which provides a means to detect carbohydrates without derivatization — Dionex CarboPac columns support simple, reliable techniques to separate sugars.

Nucleic Acid Columns

The DNAPac series of polymer-based, anion-exchange columns set the standard for oligonucleotide purity analysis, fast screening, and purification.

Amino-Acid Columns

Dionex offers two approaches to amino acid analysis: (1) anion-exchange separation by AAA-Direct in which amino acids are detected directly, without the need for derivatization, or (2) anion-exchange separation with postcolumn derivatization.

Peptide Columns

Dionex expands its Acclaim PepMap family of HPLC columns with the introduction of a 50 cm long capillary column. The increased length also increases mass loadability, which is especially beneficial when fingerprinting very low-abundant peptides.

Trap Columns

Dionex offers three trap columns for bio applications to reduce sample preparation and ensure your successful chromatographic separation.

GlycanPac Series

The Thermo Scientific™ GlycanPac™ AXR-1 and GlycanPac AXH-1 columns are high- performance, silica-based HPLC column designed for high-resolution glycan separations. They provide industry-leading resolution with a unique selectivity for biologically important glycans, either labeled or native, using either fluorescence or MS detection.