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Capillary Fast IC Columns

Optimized Separations for Faster Throughput

Many chromatographic separations have far more resolution than necessary to separate and integrate analytes of interest. Optimizing column dimensions and increasing flow rate can dramatically decrease run times while maintaining sufficient resolution. Thermo Fisher Scientific has developed a new line of Capillary Fast IC columns to facilitate separations up to 4 times faster than conventional columns. All Thermo Scientific Dionex ICS-5000 systems are designed to be compatible with Fast IC columns, which are available in standard bore, microbore, and capillary formats. Fast IC Columns

Dionex IonPac AS18-Fast Anion Exchange Column

The new Thermo Scientific Dionex IonPac AS18-Fast Capillary column offers the same selectivity as the analytical scale column, but with a reduced length of 150 mm and reduced i.d. of 0.4 mm. This column can separate the common inorganic anions in significantly less time. The capillary format offers the advantage of reduced eluent consumption, thereby lowering operating costs.  

  • Fast separation of the common inorganic anions in 4 min using the Dionex IonPac™ AS18-Fast Capillary column
  • Recommended hydroxide-selective column for inorganic anions in diverse sample matrices
  • Isocratic separation of common inorganic anions in 9 min
  • Inorganic anion and low-molecular-weight organic acids in complex sample matrices
  • Superior retention and quantification of fluoride, acetate, and formate
  • Meets performance requirements specified in US EPA Method 300.0 (A)


Figure 1. Fast separation of the common inorganic anions using an IonPac AS18-Fast Capillary column. Increasing flow rate can separate common anions 3× faster than a 250 mm long AS18 column.

Dionex IonPac CS12A-5µm Capillary Cation-Exchange Column

The new Dionex IonPac CS12A-5µm Capillary columns offer the same selectivity as their analytical-scale counterparts, but offer the advantage of reduced eluent consumption, thereby lowering operating costs.  The smaller-diameter resin technology and reduced column length provide faster analysis time, reduced eluent consumption, and increased sensitivity.


Figure 2. Fast isocratic separation of the common inorganic cations at increasing flow rates using a Dionex IonPac CS12A-5µm Capillary column.

Dionex IonSwift MAX-100 Capillary Monolithic Anion Exchange Column

Thermo Scientific Dionex IonSwift columns feature a new generation of separation media, which is uniquely designed and engineered for the separation of small molecules including organic acids and inorganic anions. The Dionex IonSwift™ MAX-100 is the first of a series of columns developed using monolith technology, and is designed to provide high-speed, high-resolution separations of organic acids and inorganic anions using a hydroxide gradient delivered by an Eluent Generator.

The unique monolith design provides:

  • Fast mass transfer
  • Fast separations
  • High throughput and improved productivity
  • Outstanding reproducibility

Figure 3. Nineteen common anions and organic acids are easily resolved using the Dionex IonSwift MAX-100 Capillary column.

Dionex CarboPac PA20 Capillary Carbohydrate Column

The Thermo Scientific Dionex CarboPac PA20 column line has been expanded to include a new 0.4 × 150 mm capillary column. As with all Dionex CarboPac PA20 columns, this new capillary format provides high-resolution separations of mono- and disaccharides with no need for derivatization. The Dionex CarboPac PA20, 0.4 × 150 mm format offers the additional advantages of higher mass sensitivity, lower required sample amounts, and significantly lower solvent use.