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Electrochemical Detection for IC

Electrochemical detection is used in combination with ion chromatography to detect the presence of compounds that contain an oxidizable or reducible moiety within their structure. Target compounds are separated by on a column and enter the electrochemical detector. The compound is either oxidized or reduced and the flow of electrons is detected as current by the electrochemical detector (ECD). The current linearly correlates to the analyte concentration.

Advantages of electrochemical detection:

  • Very selective detection method
  • High Sensitivity (femtomole detection capability)
  • Compound-specific detection can be achieved by choosing from multiple working electrode materials and corresponding pre-programmed waveforms
  • No derivatization required for detection, saving time and money

Dionex ICS-5000+ ED Electrochemical Detector

The Dionex ICS-5000+ Electrochemical Detector (ED) is flow and volume optimized and is utilized for both capillary and analytical flow rates.

Amino Acid Analysis

Analysis of amino acid content can be used to support protein or peptide structure, evaluate fragmentation strategies, or detect atypical amino acids that may be present. 

High-Performance Anion-Exchange Chromatography with Pulsed Amperometric Detection

HPAE-PAD is commonly used to determine anionic analytes without derivatization, such as carbohydrates, including mono-, di-, tri-, oligo- and polysaccharides, sugar alcohols, and amino sugars.

Conventional Working Electrodes

Electrochemical detection is used to detect compounds that contain electrochemically active moities within their structures. Conventional electrodes, in various materials, are one option for use as the working electrodes in these systems.

Disposable Working Electrodes

Disposable electrodes provide reproducible analyses, electrode-to-electrode and lot-to-lot, while maintaining good peak shape, high efficiency, and excellent sensitivity. Four types of disposable electrodes are available to detect a wide variety of analytes.