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Bio HPLC Solutions

The world's most challenging separations are protein identifications. Proteomics-based biomarker discovery demands the highest sensitivity and resolution of detail. From routine QA/QC to production of biopharmaceuticals, robust and reproducible analytical and preparative solutions are essential. Dionex has the instruments and methods that meet all the protein separation challenges, at any scale.

The Proteomics Preconcentration LC Solution is ideally suited for the analysis of in-gel digested protein samples. A reversed-phase trap column is used for sample cleanup and preconcentration of peptides. Using this method to concentrate the sample onto the trap column, conventional injection volumes can be made on nano LC columns.

To maximize sample throughput and MS utilization when performing nano and capillary LC-MS/MS for peptide sequencing and protein identification, Dionex recommends peptide preconcentration and separation using a parallel LC setup. 

Proteomics

The Proteomics Preconcentration LC Solution is ideally suited for the analysis of in-gel digested protein samples. In order to maximize the sample throughput and MS utilization when performing nano and capillary LC-MS/MS for peptide sequencing and protein identification, Dionex recommends using peptide preconcentration and separation on a parallel LC setup.

Protein Analysis

Dionex offers next generation analytical HPLC systems, combined with an outstanding array of column innovations that addresses every facet of protein analysis and characterization.

Protein Purification

Dionex offers next generation protein purification HPLC systems and an outstanding array of column innovations that addresses every facet of protein purifications.

Nucleic Acid Purification

The separation of synthetic oligonucleotides is required to ensure the products are free from contamination from incomplete synthesis, modified or improperly synthesized oligonucleotides.

Nucleic Acid Analysis

Dionex nucleic acid purification and analysis solutions ensure that the therapeutic oligonucleotides are produce and meet the most stringent quality criteria in terms of purity, potency, efficacy and safety for human use.

Amino Acid Analysis

Dionex offers next generation analytical HPLC systems, combined with outstanding array of column innovations that addresses every facet of protein analysis and characterization.