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Accelerated Solvent Extraction

Tired of spending days on sample preparation? Tired of spending countless hours on labor-intensive sample preparation steps?

Accelerated solvent extraction is a patented technique for the extraction of solid and semisolid sample matrices using common solvents at elevated temperatures and pressures. Thermo Scientific Dionex ASE systems are available in the entry-level Dionex ASE 150 system, and fully automated Dionex ASE 350.

Extractions that normally take hours can be done in minutes using accelerated solvent extraction with pH hardened pathways using Dionium components. Compared to techniques such as Soxhlet and sonication, accelerated solvent extraction generates results in a fraction of the time.

The many steps involved in sample preparation can now be automated with accelerated solvent extraction flow-through technology. Filtration and clean-up of solid samples can be achieved as part of the solvent extraction process in a single step. Accelerated solvent extraction offers a lower cost per sample than other techniques, reducing solvent consumption by up to 90%.


  • Extractions for sample sizes 1–100 g in minutes
  • Dramatic solvent reduction
  • Wide range of applications
  • Handles acidic and alkaline matrices
  • Approved for use by the U.S. EPA and CLP Program

Dionex ASE Accelerated Solvent Extractor systems can be applied to many industries:


Accelerated solvent extraction meets all of the requirements for extraction under U.S. EPA SW-846 Method 6860 Method 3545A for Pressurized Fluid Extraction, and is accepted under CLP SOW OLMO4.2.

Pharmaceutical and Natural Products

  • Active ingredients
  • Drug delivery devices and packaging

Polymers Using ASTM Method D7210

  • Oils and organic acids
  • Xylene solubles
  • Polymer additives (polyolefins, PVC)


Consumer Products

Accelerated Solvent Extraction Systems

The Dionex ASE 150 system is an entry level system for laboratories with modest throughput. The Dionex ASE 350 system is a sequential extraction system capable of automated extraction of up to 24 samples.

Accelerated Solvent Extraction Accessories

Dionex offers ASE accessories to improve productivity and allow sample tracking.

Accelerated Solvent Extraction Consumables

Thermo Scientific™ Dionex™ ASE™ Accelerated Solvent Extractor parts and accessories are designed and manufactured to meet the unique specifications of the Dionex ASE systems and meet the quality requirements of modern analytical laboratories.

Rocket Evaporator

Concentration and evaporation is an important step in achieving accurate analytical results with sample extracts. It is also labor intensive. The Thermo Scientific™ Rocket™ Evaporator automates this process, allowing the analyst to spend more time on other projects.