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Solid-Phase Extraction

The Thermo Scientific™ Dionex™ AutoTrace™ 280 Solid-Phase Extraction (SPE) instrument performs automated SPE of large-volume liquid samples for organic analysis. Liquid–liquid extractions that normally take long hours can be automated using a Dionex AutoTrace 280 SPE instrument. Extraction steps that normally require constant attention by chemists and technicians are performed automatically, and a Dionex AutoTrace 280 instrument significantly reduces sample handling compared to techniques such as separatory funnel or vacuum manifold for SPE. The tedious and time-consuming steps of liquid-liquid extraction can be greatly decreased by automating the SPE steps of condition, load, rinse, and elute. The Dionex AutoTrace 280 instrument offers a lower sample preparation cost-per-sample than other techniques by reducing solvent and labor cost by up to 90%.


  • Extractions for liquid sample sizes of 20 mL–4 L
  • Dramatic solvent reduction and reduced sample handling
  • Wide range of applications
  • Automation
  • Approved for use by many government agencies

The Dionex AutoTrace 280 instrument provides solutions for many industries:


  • Pesticides and herbicides
  • PAHs and semi-volatiles
  • PCBs
  • Dioxins and furans
  • Explosives
  • Brominated flame retardants
  • Urons (phenyl urea herbicides)

The Dionex AutoTrace 280 instrument meets requirements for Solid-Phase Extraction for U.S. EPA 500 and 600 Method series.

Pharmaceutical and Natural Products

  • Active ingredients in liquids
  • Extractables in packaged water
  • Extractables in drug delivery devices and packaging

Food and Beverage

  • Vitamins and antibiotics
  • Contaminants in bottled drinks
  • Natural products
  • Pesticides and herbicides in liquids
  • Pesticide residues
  • Herbal and dietary supplements

AutoTrace 280

The AutoTrace 280 SPE instrument is a powerful, high-throughput workstation designed for automating solid-phase extraction (SPE). The AutoTrace workstation automates the cartridge or disk conditioning, sample loading, rinsing, and eluting steps for large volume aqueous solution extractions (20 mL to 4 L).

AutoTrace Solid Phase Extraction Accessories

The SolEx™ family of Solid-Phase Extraction (SPE) cartridges are designed for fast and easy pre-concentration of contaminants prior to analysis. SPE is one of the most important techniques for sample enrichment because it overcomes many of the disadvantages of liquid-liquid extraction.